Methotrexate is an oral medication that helps relieve symptoms of severe psoriasis by slowing the growth of skin cells that cause plaques to form.

IMPORTANT SAFETY INFORMATION: Methotrexate may cause nausea, vomiting, and stomach pain. Methotrexate has rarely caused serious (sometimes fatal) side effects. For more, see Important Safety Information.

Rx Only

Prescription medication requires an online medical consultation. If appropriate, a licensed physician will prescribe a prescription treatment as part of your personalized treatment plan.


Methotrexate helps get severe psoriasis outbreaks under control by slowing down the growth rate of skin cells that cause itchy, inflamed plaques to form. Many patients start noticing clearer skin after 4-6 weeks of using methotrexate.



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Drug Facts & Safety Information
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Methotrexate helps clear up severe psoriasis by inhibiting an enzyme involved in skin cell production to prevent new plaques from forming.

Methotrexate is often prescribed for psoriasis that hasn’t responded to topical treatments. Our medical providers will evaluate your unique symptoms and medical history to determine the best psoriasis care plan for you.


How Facet Works

Yes, you really can do everything online.

1. Complete your online medical assessment Answer questions about your medical history and submit photos for our medical team to review via our secure, HIPAA-compliant platform.

2. Get your recommended treatment plan Your medical provider will select the right clinically proven medications for your skin. We will deliver them straight to your door.

3. Find lasting skin relief Easily check-in with your dedicated medical provider to track your skin’s progress and adjust your treatment plan. Most patients have 1 check-in every 3 months.

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